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Hydroquinone

Hydroquinone is an ingredient found in many topical skin bleaching creams and ointments. It is especially useful for hyperpigmented areas of the skin such as liver spots, age spots, birth marks, and freckles. It has also been used to lighten acne scars. By reducing the formation of melanin, the substance that gives skin its brown color, conditions such as chloasma or melasma (the darkening of skin around the eyes, cheeks, nose) can reduce the effects of this "mask of pregnancy" as the condition is sometimes called.

Although serious side effects are unlikely to occur, hydroquinone should be used with great care. It is essential that users read all the instructions, precautions, and potential side effects very carefully. It is also advised that people wishing to try hydroquinone products consult their health care practitioner in advance.

All hydroquinone products at ZooScape.com are intended for topical use only and should never be used internally.
 
Browse Sections:
 Summary
 Other Names
 Description
 Traditional Topical Uses
 Indications
 Actions
 Pharmacological Summary
 Research
 Precautions / Contraindications
 Interaction with Medications
 Possible Side Effects
 Dosage
 Usage
 References

Common Name
Hydroquinone
 
Other Names
Alphaquin HP, Alustra, Eldopaque, Eldopaque Forte, Eldoquin, Eldoquin Forte, Esoterica, Esoterica Sensitive Skin, Glyquin, Glyquin-XM, Lustra, Melanex, Melanol, Melpaque HP, Melquin HP, Melquin-3, Nuquin HP, Solaquin, Solaquin Forte, Viquin Forte, Alpha-Hydroquinone, Hydroquinol, Quinol, Benzoquinol, P-benzenediol, 1,4-Benzenediol, P-Dihydroxybenzene, P-Hydroxyphenol, P-Dioxobenzene, 1,4-Dihydroxybenzene, Dihydroquinone, Pyrogentistic Acid, Quinnone, Aida, Aarctuvin, Eldoquin, Eldopaque, Phiaquin, Tecquinol, Tenox HQ, Tequinol.

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Scientific Name / Nomenclature
C6H6O2
 
Description
Hydroquinone (hye-droe-QUIH-none) is applied to the skin to lighten areas that have darkened (hyperpigmented). This is a common side effect of many drugs including birth control drugs and discontinuation of such drugs will stop but not reverse the hyperpigmentation. Hydroquinone will work best if you avoid excessive exposure to sunlight and wear sunscreens and protective clothing.

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Traditional Topical Uses
All hydroquinone products at ZooScape.com are intended for topical use only and should never be used internally.

Hydroquinone decreases the formation of melanin in the skin. Melanin is the pigment in skin that gives it a brown color. Hydroquinone topical is used to lighten areas of darkened skin such as freckles, age spots, chloasma, and melasma. Hydroquinone topical may also be used for purposes other than those listed here.

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Indications
Primary Indications: Hyperpigmentation (Age Spots, Liver Spots & Freckles), Melasma / Chloasma ("Mask of Pregnancy"), Stretch Marks, Scars, Acne

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Actions
Skin Lightening or Bleaching

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Pharmacological Summary
Hydroquinone works by decreasing the production and increasing the breakdown of melanosomes (melanin pigment granules) in the skin's pigment cells (melanocytes). The inhibition of melanogenesis is achieved by interrupting one or more steps in the tyrosine-tyrosinase pathway the enzyme needed to make melanin.

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Research
"Hydroquinone Combination Cream Combats PIH"

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Precautions / Contraindications
Avoid exposure to sunlight or artificial UV rays (e.g., sunlamps). Darkening of the skin may occur with exposure to sunlight or artificial UV light. Use a sunscreen (minimum SPF 15) and wear protective clothing when exposure to the sun or UV rays is unavoidable.

Do not use hydroquinone topical on skin that is sunburned, windburned, dry, chapped, or irritated, or on an open wound. It could make these conditions worse. Wait until these conditions have healed before applying hydroquinone topical.

What should I discuss with my healthcare provider before using hydroquinone topical?
  • Do not use hydroquinone topical on skin that is sunburned, windburned, dry, chapped, or irritated, or on an open wound. It could make these conditions worse. Wait until these conditions have healed before applying hydroquinone topical.
  • Before using hydroquinone topical, talk to your doctor if you have liver or kidney disease, use other topical medications on the affected area, have allergies to medications, or have other medical problems. You may not be able to use hydroquinone topical, or you may require a dosage adjustment or special monitoring during treatment.
  • It is not known whether hydroquinone topical will be harmful to an unborn baby. Do not use hydroquinone topical without first talking to your doctor if you are pregnant or could become pregnant during treatment.
  • It is not known whether hydroquinone will be harmful to a nursing baby. Do not use hydroquinone topical without first talking to your doctor if you are breast-feeding a baby.
What should I avoid while using hydroquinone topical?
  • Avoid exposure to sunlight or artificial UV rays (e.g., sunlamps). Darkening of the skin may occur with exposure to sunlight or artificial UV light. Use a sunscreen (minimum SPF 15) and wear protective clothing when exposure to the sun or UV rays is unavoidable.
  • Do not use hydroquinone topical on skin that is sunburned, windburned, dry, chapped, or irritated, or on an open wound. It could make these conditions worse. Wait until these conditions have healed before applying hydroquinone topical.
  • The skin may be more sensitive to weather extremes such as cold and wind. Protect the skin with clothing and use a moisturizing cream or lotion as needed.
  • Avoid using other topical products on the same area at the same time unless directed to do so by your doctor. Use caution and talk to your doctor before using hydroquinone topical if you are also using other topical products with a strong drying effect on the skin, products with high concentrations of alcohol, astringents, spices or lime, or other preparations or processes that may dry or irritate the skin.
  • Do not use hydroquinone topical with benzoyl peroxide, hydrogen peroxide, or other peroxide products. A temporary dark staining of the skin may occur. If hydroquinone topical is accidentally used with a product that contains peroxide, wash the skin with soap and water to remove the staining.
  • Keep out of reach of children.


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Interaction with Medications
What other drugs will affect hydroquinone topical?
  • Do not use hydroquinone topical with benzoyl peroxide, hydrogen peroxide, or other peroxide products. A temporary dark staining of the skin may occur. If hydroquinone topical is accidentally used with a product that contains peroxide, wash the skin with soap and water to remove the staining.
  • Avoid using other topical products on the same area at the same time unless directed to do so by your doctor. Use caution and talk to your doctor before using hydroquinone topical if you are also using other topical products with a strong drying effect on the skin, products with high concentrations of alcohol, astringents, spices or lime, or other preparations or processes that may dry or irritate the skin.
  • Drugs other than those listed here may also interact with hydroquinone topical. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.


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Possible Side Effects
What are the possible side effects of hydroquinone topical?
  • Serious side effects are not likely to occur. Stop using hydroquinone topical and seek emergency medical attention or contact your doctor if you experience:

    • an allergic reaction (shortness of breath; closing of the throat; swelling of the lips, face, or tongue; or hives); or

    • a rash.

    More commonly, some burning, stinging, itching, redness, or irritation, of the treated area may be experienced. If these side effects are excessive, talk to your doctor. You may need a lower dose or less frequent application of hydroquinone topical.

  • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


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Dosage
Use as directed on the label or as advised by your health care professional.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and apply only the next regularly scheduled dose. Do not use a double dose of the medication.

What happens if I overdose?

An overdose of this medication is unlikely to be harmful. If you do suspect an overdose, or if hydroquinone topical has been ingested, call an emergency room or poison control left for advice.

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Usage
How should I use hydroquinone topical?
  • Use hydroquinone topical exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Hydroquinone topical is for external use only.
  • Wash your hands before and after applying this medication, unless the treated area involves the hands.
  • Apply the medication to clean, dry skin. Apply just enough medication to cover the affected area. Avoid application of the medication to unaffected, surrounding skin. Rub in the medication gently and completely.
  • Do not apply hydroquinone topical to the eyes, lips, or inside of the nose or mouth. Accidental application of hydroquinone topical to the lips may cause numbness of the lips and/ or a medicinal taste in the mouth. If the medication is accidentally applied to any of these areas, rinse with water. Seek medical advice if the medication gets in the eyes.
  • It is important to use hydroquinone topical regularly to get the most benefit.
  • Store hydroquinone topical at room temperature away from moisture and heat between 15 and 30 degrees C (59 and 86 degrees F); do not freeze.


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References
Our thanks to the following information resources: Drug Information Online (Drugs.com), University of Oxford Physical and Theoretical Chemistry Laboratory (ptcl.chem.ox.ac.uk), GlobalRx.com, and DrugDigest.org.

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3 total products
Hydroquinone   (Read all about Hydroquinone.)
Hydroquinone - Personal - Hydroquinone USP Bleaching Salve / Ointment (2%)
Hydroquinone - Personal - Hydroquinone USP Bleaching Salve / Ointment (2%)
2 oz / 57 g
Preserve Your Pristine, Healthy Skin!

21.31 US
More Info
Hydroquinone - Personal - Hydroquinone USP Bleaching Cream (2%)
Hydroquinone - Personal - Hydroquinone USP Bleaching Cream (2%)
2 oz / 57 g
Preserve Your Pristine, Healthy Skin!

18.20 US
More Info
Hydroquinone - Personal - Hydroquinone USP Bleaching Gel (2%)
Hydroquinone - Personal - Hydroquinone USP Bleaching Gel (2%)
2 oz / 57 g
Preserve Your Pristine, Healthy Skin!

20.84 US
More Info


These statements have not been evaluated by the Food and Drug Administration (FDA). Products are intended to support general well being and are not intended to treat, diagnose, mitigate, prevent, or cure any condition or disease. If conditions persist, please seek advice from your medical doctor.



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