| | | | Pau D'Arco | | | Pau d'arco's history and uses date back to early South American native
Indians with scientific documentations starting in the 1800's. The active
constituent, lapachol, was isolated in 1884 and synthesized in 1927, so
pau d'arco is not a recent discovery. Research has shown that a
naphthoquinone identified as lapachol, has anti-bacterial, anti-viral, and
anti-fungal properties. This has led to the use of pau d'arco in the
treatment of infectious and viral conditions such as candida, thrush, and
the herpes simplex virus.
Cancer research in the `60s and `70s
showed that pau d'arco may prevent, delay, or treat cancer; but the oral
doses needed to reach useful levels in the blood may cause severe side
effects according to researchers. Proponents of the use of pau d'arco
believe that the inner bark in its entirety must be evaluated - not simply
one isolated component. There may indeed be constituents that modify the
effect of the toxic active ingredient on living organisms.
At
present, pau d'arco remains controversial and many consider research
findings to be inconsistent and inconclusive. It is widely agreed that
further properly controlled studies are required to determine any
potential efficacy and toxicity on human beings taking dried extracts of
this exotic and mysterious herb.
| |
| Common Name | | | Pau D'Arco | | | Botanical Latin Name / Classification | | | Tabebuia impetiginosa | | | Parts Used | | | Inner bark | | | Description | | | Pau d'arco, also known as lapacho, is an evergreen tree, native to the
rain forests and mountains of Paraguay, Argentina and Brazil. This
impressive tree can grow to 125 feet and is the proud bearer of beautiful
trumpet like flowers, but it is the inner bark which has been used
therapeutically for thousands of years. Its extremely hard wood makes it
resistant to disease and decay. In recent years, however, there has been
an increasing demand for pau d'arco and, as a result, the trees are in
danger of becoming extinct.
Browse Sections | View Pau D'Arco products | | | Traditional Internal Uses | | | To treat a host of ills ranging from fungal infections to the common cold,
traditional healers in South and Central America have long brewed a tea
made from the inner bark of a native evergreen tree of the Tabebuia
species. They reportedly still use pau d'arco bark to treat cancer, lupus,
infectious diseases, wounds, and many other health conditions.1 Caribbean
folk healers use the leaf of this tree in addition to the bark for the
treatment of backache, toothache, sexually transmitted diseases, and as an
aphrodisiac.
This healing brew, variously referred to as pau d'arco
or Taheebo, is readily available in North American health-food stores and
sold as a "cure" for cancer and numerous other ills (including
diabetes, warts, and vaginal yeast infections). Whether pau d'arco
actually works for any of these conditions is unclear and the subject of
ongoing confusion and controversy.
Today, the majority of
practicing herbalists cite both a lack of proven effectiveness and the
toxicity that's associated with high doses as reasons for recommending
against taking pau d'arco to treat cancer, although some consider it
useful to take as an immune booster while fighting the disease.
Pau
d'arco has also been found to be useful for a number of other disorders.
Browse Sections | View Pau D'Arco products | | | Traditional Topical Uses | | | Pau d'arco has been used for treating vaginal yeast infections.
Anti-inflammatory and anti-fungal actions in pau d'arco appear to be
effective in restoring the vagina to a normal state. Herbalists recommend
a pau d'arco tea douche for this purpose.
It is also used to
eliminate warts. Pau d'arco applied directly to warts allows the antiviral
compounds in the bark to get to work. Once diluted, pau d'arco is even
safe to use on genital warts. However, be sure to see a doctor if you
develop a genital wart; such warts are not only transmitted sexually (and
partners should be protected), but can cause serious complications in a
woman's reproductive organs.
Browse Sections | View Pau D'Arco products | | | Indications | | | Primary Indications: Yeast Infection (Candida Albicans), Vaginal Infection / Discharge (Vaginitis), Thrush, Herpes (Genital), Fungal Infections, Macular Degeneration (AMD), Athlete's Foot, Skin Disorders, Warts
Secondary Indications: Prostatitis - Prostate Inflammation, Arthritis, Rheumatism, Gastrointestinal Disorders, Dysentery, Flu / Influenza, Parasites / Parasitic Infections, Worms, Ringworms, Tapeworms, Pinworms, Malaria, Immunity / Immune Disorders
Other Indications: HIV / AIDS Support, Chronic Fatigue Syndrome (CFS), Bronchitis, Lupus, Diabetes (Type I / Type II), Food Allergies / Sensitivities, Leprosy, Syphilis, Cancer / Cancer Prevention, Snake Bites, Back Pain, Tooth Decay (Cavities / Caries), Sexual Dysfunction
Browse Sections | View Pau D'Arco products | | | Actions | | | Anti-Infectious, Anti-Inflammatory, Antibacterial, Anticancer / Antitumor, Antifungal, Antioxidant, Antiparasitic, Antipsoriatic, Antiviral, Diuretic, Immunoactive / Immunomodulatory / Immunostimulative
Browse Sections | View Pau D'Arco products | | | Constituents / Nutrients | | | Lapachol and beta-lapachone (known collectively as naphthaquinones) are
two primary active compounds in pau d'arco. According to laboratory tests,
both have anti-fungal properties as potent as ketoconazole, a common
antifungal drug.2 However, amounts of these constituents needed to exert
an antifungal effect may be toxic to humans. Although these compounds also
have anticancer properties according to test tube studies, the effective
amount for this effect may also be toxic.3 4 Therefore, pau d'arco cannot
currently be recommended as a treatment for cancer.
Browse Sections | View Pau D'Arco products | | | Pharmacological Summary | | | Due to the lack of clinical research, it is difficult to make any
recommendations with certainty regarding the medicinal properties and uses
of this interesting plant.
Promising laboratory test results on
animals led to trials on humans in the 1970s, however side effects of
lapachol in test patients were deemed too severe.
Scientific
evidence does point to definite anti-bacterial, anti-viral, and
anti-fungal properties of pau d'arco. However, some believe that is
uncertain whether or not the potentially serious side effects caused by
dose levels necessary to produce medical effects make oral pau d'arco too
risky to recommend for use in any medical condition.
Skeptics point
to the inconsistent results of the isolated active ingredient, lapachol,
in laboratory studies. Advocates of the use of pau d'arco argue that the
whole bark produces different effects, due to the combined action of
dozens of chemicals that cannot be expected from a single compound.
Consequently, any definitive statements regarding the efficacy or toxicity
of pau d'arco supplements on humans cannot be made at present.
Browse Sections | View Pau D'Arco products | | | Scientific Research and Pharmacologicial Actions | | | While many health claims for pau d'arco have not been
substantiated--including the far-reaching assertion that it can
"cure" various forms of cancer--there are some positive
findings.
During the 1970s the National Cancer Institute at the
National Institutes of Health (NIH) actually tested pau d'arco in human
studies after finding that it shrank cancerous malignancies in animals.
Researchers discovered that while large doses of one of the herb's key
ingredients (lapachol) could destroy cancer cells, the side effects
produced in the patients (blood-clotting abnormalities, anemia, nausea)
were too severe. Further studies were abandoned.
Researchers have
detected in the inner bark of the Tabebuia trees a handful of powerful
infection-fighting compounds called naphthoquinones. One of these
substances (lapachol) seems to be particularly potent. Naphthoquinones
appear to help kill certain disease-causing bacteria, viruses, and fungi,
partially justifying the name given to this herbal remedy
("tajy," meaning to have strength and vigor) by the Guarani and
Tupi tribes in South America.
In addition, laboratory studies have
demonstrated that pau d'arco has anti-fungal properities on par with a
common anti-fungal prescription drug (ketoconazole). This action likely
explains its effectiveness for vaginal infections (caused by the yeast
Candida), as well as for fighting the fungi responsible for athlete's
foot, jock itch, and other common fungal skin infections. (Commercially
available products are available for this purpose.)
Note: It
is important to consider that the aforementioned studies involved isolated
lapachol - not the collective compounds of pau d'arco. It may be that a
group of compounds, unique to pau d'arco, enhance efficacy and mitigate
toxicity or vice versa. Until further testing occurs, studies that isolate
lapachol alone must be viewed with this consideration in mind.
Browse Sections | View Pau D'Arco products | | | Research | | | "My Experience With Pau D'Arco and Protozoans"
Browse Sections | View Pau D'Arco products | | | Precautions / Contraindications | | | Some American studies have shown pau d'arco to cause nausea and diarrhea
in very high doses. It has also been noted that when using this herb
initially, some may experience slight nausea which is usually associated
with the detoxification process, but this is a positive sign.
Because pau d'arco may decrease the blood's ability to clot, it should not
be used by individuals who have bleeding disorders such as
hemophilia.
The American FDA (Food and Drugs Administration) tested
pau d'arco for toxicity in 1981 and passed it.
Browse Sections | View Pau D'Arco products | | | Interaction with Medications | | | Prescription Drugs
In studies and case reports, pau d'arco
has been shown to increase the time blood needs to clot. When it is taken
with antiplatelet or anticoagulant drugs, the effect of the drug may be
increased, resulting in uncontrolled bleeding.- Antiplatelets
include Plavix and Ticlid
- Anticoagulants include heparin and
warfarin
Non-Prescription Drugs
Orally, pau d'arco
may decrease the ability of blood to clot after an injury. Aspirin can
also delay clotting, so pau d'arco should not be taken orally at the same
time as aspirin.
Herbal Products
Theoretically, if
pau d'arco is used with other herbs that affect blood clotting, bleeding
may occur. Some of the most common herbal products that might inhibit
blood clotting are:- Danshen
- Devil's
Claw
- Eleuthero
- Garlic
- Ginger (in high
amounts)
- Ginkgo
- Horse Chestnut
- Panax
Ginseng
- Papain
- Red Clover
- Saw
Palmetto
Some interactions between herbal products and
medications can be more severe than others. The best way for you to avoid
harmful interactions is to tell your doctor and/or pharmacist what
medications you are currently taking, including any over-the-counter
products, vitamins, and herbals.
One case report exists of a
28-year-old man who died of liver failure after taking unspecified amounts
of pau d'arco, scullcap, and zinc.9 It appears likely that this may have
been a case of adulteration of scullcap with germander.10
Browse Sections | View Pau D'Arco products | | | Possible Side Effects | | | High amounts (several grams daily over several days) of lapachol can cause
uncontrolled bleeding, nausea, and vomiting.7 Use of the whole bark is
typically safer than isolated lapachol-side effects have included nausea
and gastrointestinal upset.8
Pregnant or breast-feeding women
should avoid use of pau d'arco.
Browse Sections | View Pau D'Arco products | | | Dosage | | | A traditional recommendation is 2-3 teaspoons (10-15 grams) of the inner
bark simmered in a pint (500 mL) of water for fifteen minutes three times
per day.5 However, the naphthaquinones believed to give pau d'arco its
major effects are very poorly extracted in water, so teas are not usually
recommended in modern herbal medicine.6 Capsules or tablets providing
400-600 mg of powdered bark can be taken three times per day. A tincture,
1/8-1/4 teaspoon (0.5-1 ml) three times per day, can also be used.
Browse Sections | View Pau D'Arco products | | | References | | | 1. Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press,
1985, 470-1.
2. Guiraud P, Steiman R, Campos-Takaki GM, et al. Comparison of
antibacterial and antifungal activities of lapachol and beta-lapachone.
Planta Med 1994;60:373-4.
3. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals.
Binghamton, NY: Pharmaceutical Products Press, 1994, 180.
4. Oswald EH. Lapacho. Br J Phytother 1993/4;3:112-7.
5. Foster S. Herbs for Your Health. Loveland, CO: Interweave Press, 1996,
70-1.
6. Awang DVC, Dawson BA, Ethier JC, et al. Naphthoquinone constituents of
commercial lapacho/pau d'arco/taheebo products. J Herbs Spices Med Plants
1994;2:27-43.
7. Duke JA. CRC Handbook of Medicinal Herbs. Boca Raton, FL: CRC Press,
1985, 470-1.
8. Oswald EH. Lapacho. Br J Phytother 1993/4;3:112-7.
9. Hullar TE, Sapers BL, Ridker PM, et al. Herbal toxicity and fatal
hepatic failure [letter]. Am J Med 1999;106:267-8.
10. Brown D. A case of fatal liver failure associated with herbal
products. Healthnotes Rev Complement Integrative Med
1999;6:176-7.
Our thanks to the following information
resources: WholehealthMD.com, Vitacost.com, UMM.edu, and
DrugDigest.org.
Browse Sections | View Pau D'Arco products | |
| | 16 total products | | | Pau D'Arco (Read all about Pau D'Arco.)
Botanical Latin Name: Tabebuia impetiginosa Plant Part: Inner bark | |
| | |  |
|
Pau D'Arco - Health - Pau D'Arco Tea (Loose) 4 oz / 114 g
$9.45 US Was: 10.27 US In Stock - Ships Today! More Info
| |
Pau D'Arco - Health - Pau D'Arco Tea (Loose) 8 oz / 227 g
$13.68 US Was: 14.87 US In Stock - Ships Today! More Info
| |
Pau D'Arco - Health - Pau D'Arco Tea 25 tea bags
$10.09 US Was: 10.97 US In Stock - Ships Today! More Info
| |
Pau D'Arco - Health - Pau D'Arco Tea 50 tea bags An Important Part of Tribal Healing For Thousands of Years.
$14.90 US Was: 16.20 US Usually ships in 1-3 days. More Info
| |  |
|
Pau D'Arco - Health - Pau D'Arco - Liquid Extract / Tincture (1:5) - Alcohol-Free 1 fl oz / 30 mL Gallbladder and Digestive Support!
$8.74 US Was: 9.50 US Usually ships in 1-3 days. More Info
| |
Pau D'Arco - Health - Pau D'Arco - Liquid Extract / Tincture (1:5) - Strawberry Flavored Alcohol-Free 1 fl oz / 30 mL Gallbladder and Digestive Support!
$8.74 US Was: 9.50 US Usually ships in 1-3 days. More Info
| |
Pau D'Arco - Health - Pau D'Arco - Salve / Ointment 2 oz / 57 g
$14.47 US Was: 15.73 US In Stock - Ships Today! More Info
| |
Pau D'Arco - Health - Pau D'Arco - Cream 2 oz / 57 g
$12.68 US Was: 13.78 US In Stock - Ships Today! More Info
| |  |
|
Pau D'Arco - Health - Pau D'Arco - Liquid Extract / Tincture (1:5) - Chocolate Flavored Alcohol-Free 1 fl oz / 30 mL Gallbladder and Digestive Support!
$8.74 US Was: 9.50 US Usually ships in 1-3 days. More Info
| |
Pau D'Arco - Health - Pau D'Arco - Liquid Extract / Tincture (1:5) - Vanilla Flavored Alcohol-Free 1 fl oz / 30 mL Gallbladder and Digestive Support!
$8.74 US Was: 9.50 US Usually ships in 1-3 days. More Info
| |
Pau D'Arco - Health - Pau D'Arco - Liquid Extract / Tincture (1:5) - Mint Flavored Alcohol-Free 1 fl oz / 30 mL Gallbladder and Digestive Support!
$8.74 US Was: 9.50 US Usually ships in 1-3 days. More Info
| |
Pau D'Arco - Health - Pau D'Arco Bark Powder 4 oz / 114 g
$11.90 US Was: 12.93 US In Stock - Ships Today! More Info
| |  |  |  | 1 2 Next  |
These statements have not been evaluated by the Food and Drug Administration (FDA). Products are intended to support general well being and are not intended to treat, diagnose, mitigate, prevent, or cure any condition or disease. If conditions persist, please seek advice from your medical doctor.
|