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Flax Seed Oil
Browse Sections:
 Summary
 Other Names
 Traditional Internal Uses
 Pharmacological Summary
 Precautions / Contraindications
 Interaction with Medications
 Possible Side Effects
 Dosage
 References

Common Name
Flax Seed Oil
 
Botanical Latin Name / Classification
Linum Usitatissimum
 
Other Names
Linseed Oil, Flax Oil, Flaxseed Oil

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Traditional Internal Uses
Flaxseed oil is used to supplement the daily intake of the omega-3 essential fatty acid nutrient. The seed oil is essentially 58% alpha-linolenic acid, which is the starting fatty acid for the omega-3 family. (The alpha- designation is used to separate this linolenic acid from gamma-linolenic acid in the omega-6 family.)

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Pharmacological Summary
Flaxseed oil is the best land-based source of omega-3 fatty acids. In the body, flaxseed alpha-linolenic acid is destined to become EPA and DHA, the actual fatty acids of critical importance. Only ocean fish can compete as a source of ready made EPA and DHA. However, not everyone enjoys ocean fish on a regular basis, and flaxseed oil is able to meet the omega-3 needs of those who do not eat fish. But, the dietary presence of magnesium, zinc, vitamin B6, vitamin C and niacin/niacinamide in adequate levels is required to facilitate the cascade. For this reason, some people may be better advised to use Salmon oil. Older people may not make the cascade transformations to EPA and DHA well, because of diet and because of age-related metabolic decline.

EPA is important in the control of the natural and purposeful inflammatory process and its deficiency allows the omega-6 arachidonic acid pro-inflammatory component to drive inflammation into chronic conditions that can develop into pathological states. Since inflammation is a fire that must always be controlled, the body can be harmed by an EPA short fall in the regulatory process.(3) Research has shown that men with the highest levels of inflammation are three times as likely to suffer a heart attack and two times as likely to have a stroke.(4) A greater dietary supply of EPA via regular ocean fish consumption or supplemented flaxseed or ocean fish oils would reduce the risk of stroke and heart attack.

Earlier research asked the question, does omega-3 fatty acid lower blood pressure. The answer from one investigation was that a 1 percent increase in linolenic acid in the blood was associated with a 5 mm reduction in pressure.(5) Flaxseed oil may not demonstrate any significant reduction in blood pressure unless consumed in large quantities, such as 1 to 2 tablespoons per day.

The omega-3 fatty acid EPA is credited with lowering the propensity to blood clot. This is usually a desirable condition, since most heart attacks are caused by inappropriate blood clotting. A faithful use of flaxseed oil would be beneficial in this regard, and would be a natural answer to those who advocate that everyone should use ASA as protection against heart attack. This efficacy of EPA is demonstrable in the consideration that the Inuit Eskimos, who follow their ancestry diet of high EPA intake through fish and marine mammals, are known to be "bleeders", while North Americans, who consume high quantities of omega-6 oils, are known to be "clotters". EPA is associated with reduced platelet stickiness and reduced fibrinogen production.(6)

The 1989 English Diet and Reinfarction Trial (DART) looked at 2000 men who were all recovering from heart attack. The participants were divided into three groups based on dietary differences: Group 1 received a high fiber diet, Group 2 received a diet low in saturated fat and relatively high in omega-6, and Group 3 received a diet high in omega-3 as either fish or omega-3 supplementation. Those in Group 3 demonstrated a 29 percent lower death rate compared to the other two Groups.(7)

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Precautions / Contraindications
Precaution

Flaxseed oil may potentiate anticoagulation medication. Flaxseed oil should be used when Evening Primrose oil is used to favor a more optimal balance between omega-6 and omega-3 oils. The recommended ratio is one part of flaxseed oil for every part of Evening Primrose oil.

Contraindications

Flaxseed oil supplementation with its linolenic acid is contraindicated in anticoagulant therapy unless prescribed under the guidance of a physician.

Large amounts of flaxseed oil can potentiate anticoagulation therapy by increasing the endogenous level of EPA and the resultant eicosanoids that modulated blood clotting, and could be a confounding factor in the establishment of coagulation control.

The minimum daily requirement of this omega-3 essential fatty acid nutrient is regarded to be not less than 0.5 % of daily calories.(8) Flaxseed oil is comprised of essentially 58 percent of linolenic acid. A diet of 2000 calories would require a minimum of 10 calories of linolenic acid. A one gram capsule of flaxseed oil is essentially 5 calories of linolenic acid, so that 2 capsules would meet the minimum daily requirement, assuming no other dietary supply was consumed. Those consuming ocean fish three times per week would have no need to supplement with flaxseed oil.

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Interaction with Medications
The conversion of alpha-linolenic acid into the beneficial EPA and DHA requires the dietary presence of magnesium, zinc, vitamin B6, vitamin C and niacin/niacinamide in adequate levels to facilitate the cascade.(3)

Flaxseed oil, and vitamin E are natural blood thinners. Those taking pharmaceutical blood thinners or ASA frequently should discuss supplementation with their physician for dosage advice.

Diabetics using flaxseed and Evening Primrose oil may experience better blood sugar control that gradually reduces their insulin requirement, and should be made aware that these changes can occur, in order to avoid hypoglycemic episodes.

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Possible Side Effects
Flaxseed oil is not normally associated with adverse or toxic effects.(1-3)

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Dosage
Recommended amount is 1-3 softgels, 3 times daily or as directed by a physician.

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References
1. Murray, Michael T., Encyclopedia of Nutritional Supplementation, Prima Publishing, Rocklin ,CA, 1996
2. Simopoulos, Artemis P., Robinson, Jo, The Omega Plan, HarperCollins Publishers, New York, 1998
3. Erasmus, Udo, Fats That Heal Fats That Kill, Alive Books, Burnaby, BC, 1993
4. Ridker, P.M., et al, "Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men", New England Journal of Medicine,336(14): 973-979, 1997
5. Berry, M.E.,, Hirsch, J., Does dietary linolenic acid influence blood pressure?", American Journal of Clinical Nutrition, 44: 336-340, 1986
6. Radack, K., et al, "Dietary supplementation with low-dose fish oils lowers fibrinogen levels: A randomized, double-blind controlled study", Annalsof Internal Medicine, 11(9): 757-758, 1989
7. Burr, M.L., et al, "Effects of changes in fat, fish, and fiber intakes on death and myocardial reinfarction: Diet and Reinfaction Trial(DART)", Lancet, 757-761, Sept, 30, 1989
8. The Report of the Scientific Review Committee, Nutrition Recommendations, Canadian Government Publishing Centre, Ottawa, 1990

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Botanical Latin Name: Linum Usitatissimum
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Flax Seed Oil - Health - 30 Day Fabulax Bowel Cleanse
Flax Seed Oil - Health - 30 Day Fabulax Bowel Cleanse

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These statements have not been evaluated by the Food and Drug Administration (FDA). Products are intended to support general well being and are not intended to treat, diagnose, mitigate, prevent, or cure any condition or disease. If conditions persist, please seek advice from your medical doctor.



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