| Contributors | |
| Preface | |
| Pt. 1 | Bladder Cancer | 1 |
| 1 | Incidence, etiology, epidemiology and genetics | 3 |
| 2 | Natural history | 11 |
| 3 | Pathology | 17 |
| 4 | Bladder carcinoma presentation, diagnosis and staging | 37 |
| 5 | Treatment of superficial transitional cell carcinoma | |
| 5.1 | Surgical treatment of superficial transitional cell carcinoma | 42 |
| 5.2 | Intravesical treatment of superficial transitional cell carcinoma | 45 |
| 5.3 | The follow up of superficial bladder cancer | 52 |
| 6 | Treatment of carcinoma in situ | 57 |
| 7 | Treatment of invasive transitional cell carcinoma | |
| 7.1 | Surgical ablation of invasive transitional cell carcinoma of the bladder | 67 |
| 7.2 | Urinary diversion and bladder replacement | 76 |
| 7.3 | Bladder preserving treatment for muscle invasive bladder cancer | 85 |
| 7.4 | Systemic chemotherapy for transitional cell carcinoma of the urinary tract | 88 |
| 7.5 | Radiotherapy in the management of bladder cancer | 94 |
| 8 | Adenocarninoma of the bladder | 97 |
| 9 | Squamous tumors of the urinary bladder | 103 |
| Pt. 2 | Prostate Cancer | 109 |
| 10 | Epidemiology and etiology | 111 |
| 11 | Natural history | 117 |
| 12 | Pathology | 127 |
| 13 | Presentation and diagnosis | 139 |
| 14 | Staging | 151 |
| 15 | Treatment of early organ-confined disease | |
| 15.1 | Issues and options: patient and tumor factors | 162 |
| 15.2 | Watchful-waiting | 164 |
| 15.3 | Prostate cancer treatment: radical prostatectomy for early organ-confined disease | 167 |
| 15.4 | Radiotherapy for organ-confined prostate cancer | 176 |
| 16 | Treatment of locally advanced disease | |
| 16.1 | Hormonal downstaging: myth or reality? | 180 |
| 16.2 | Surgery: Is there a rationale? | 186 |
| 16.3 | Radiation Therapy | 190 |
| 16.4 | Locally advanced prostate cancer - hormonal treatment | 203 |
| 17 | Treatment of metastatic prostate cancer | |
| 17.1 | Endocrine therapy | |
| F. Rabbani | 210 |
| 17.2 | Immediate versus deferred hormonal treatment | 226 |
| 17.3 | Radiation therapy | 233 |
| 17.4 | Strontium[superscript 89] in metastatic disease | 242 |
| 17.5 | The use of bisphosphonates in prostate carcinoma metastatic to the skeleton | 244 |
| 17.6 | The role of monoclonal antibody imaging in the management of prostate cancer | 248 |
| 17.7 | Chemotherapy in patients with androgen independent prostate cancer | 254 |
| 18 | Management of sequelae, voiding dysfunction and renal failure | 259 |
| Pt. 3 | Upper Urinary Tract, Adrenal and Retroperitoneal Tumors | 271 |
| 19 | Renal cell carcinoma: Incidence, etiology, epidemiology and genetics | 273 |
| 20 | Pathology of renal tumors | 277 |
| 21 | Renal cell carcinoma: Presentation, diagnosis and staging | 285 |
| 22 | Surgical treatment of renal cell carcinoma | |
| 22.1 | Radical nephrectomy | 296 |
| 22.2 | Surgery for neoplastic involvement of the renal vein and inferior vena cava | 300 |
| 22.3 | Partial radical nephrectomy | 304 |
| 22.4 | Von Hippel-Lindau disease | 306 |
| 23 | Minimally invasive therapy | |
| 23.1 | Focused ultrasound ablation | 311 |
| 23.2 | Focused microwave ablation and cryotherapy | 316 |
| 23.3 | Laparoscopic surgery | 316 |
| 24 | Metastatic renal cancer | |
| 24.1 | The role of surgery and tumor embolization | 325 |
| 24.2 | The role of immunotherapy | 329 |
| 24.3 | The role of chemotherapy | 337 |
| 25 | Transitional cell carcinoma of the upper urinary tract: Incidence, etiology, epidemiology and genetics | 349 |
| 26 | Transitional cell carcinoma of the upper urinary tract: Presentation, diagnosis and staging | 355 |
| 27 | Transitional cell carcinoma of the upper urinary tract: Pathology | 361 |
| 28 | Transitional cell carcinoma of the upper urinary tract: Surgical treatment | |
| 28.1 | Nephro-ureterectomy and partial ureterectomy | 368 |
| 28.2 | Percutaneous, ureteroscopic resection and novel approaches | 372 |
| 29 | Chemotherapy and immunotherapy for upper urinary tract transitional cell carcinoma | 379 |
| 30 | Rare renal tumors | 383 |
| 31 | Adrenal tumors | 389 |
| 32 | Retroperitoneal malignancies and processes | 397 |
| 33 | Pathology of adrenal and retroperitoneal tumors | 407 |
| Pt. 4 | Testicular Cancer | 413 |
| 34 | Incidence, etiology, epidemiology and genetics | 415 |
| 35 | Pathology | 423 |
| 36 | Presentation, diagnosis and staging | 431 |
| 37 | Carcinoma in situ | 435 |
| 38 | Non-seminomatous germ-cell tumors | |
| 38.1 | Germ cell tumors: surveillance and adjuvant chemotherapy | 440 |
| 38.2 | Surgical treatment | 445 |
| 38.3 | Practical approaches to the use of chemotherapy | 452 |
| 39 | Seminomatious germ cell tumor | |
| 39.1 | Treatment of seminomas | 462 |
| 39.2 | Radiotherapy | 463 |
| 39.3 | Background, rationale and results from use of chemotherapy in metastatic and localized seminoma | 467 |
| 40 | Non-germ cell testicular tumors | 475 |
| Pt. 5 | Spermatic Cord and Scrotal Cancer | 479 |
| 41 | Tumors of the spermatic cord | |
| 41.1 | Epidemiology and etiology | 482 |
| 41.2 | Presentation, staging and diagnosis | 482 |
| 41.3 | Pathology of malignant tumors of the spermatic cord | 483 |
| 41.4 | Paratesticular sarcomas | 486 |
| 41.5 | Radiotherapy | 487 |
| 41.6 | Systemic chemotherapy | 488 |
| 42 | Tumors of the scrotum | |
| 42.1 | Epidemiology and etiology | 489 |
| 42.2 | Presentation, diagnosis & staging of squamous cell carcinoma | 490 |
| 42.3 | Pathology of malignant tumors of the scrotum | 491 |
| 42.4 | Surgical management of scrotal carcinoma | 493 |
| 42.5 | Radiotherapy for scrotal carcinoma | 494 |
| 42.6 | Chemotherapy for scrotal carcinoma | 495 |
| Pt. 6 | Carcinoma of the Penis | 497 |
| 43 | Incidence, etiology and epidemiology | 499 |
| 44 | Presentation, diagnosis and staging | 503 |
| 45 | Pathology of carcinoma of the penis | 507 |
| 46 | Surgical Management | |
| 46.1 | Surgical Management | 515 |
| 46.2 | The role of radiotherapy in the management of squamous carcinoma | 519 |
| 46.3 | Chemotherapy | 521 |
| Pt. 7 | Carcinoma of the Urethra | 523 |
| 47 | Carcinoma of the urethra | 525 |
| 48 | Pathology of urethral carcinoma | 529 |
| 49 | Treatment | 535 |
| 49.1 | Surgery | 538 |
| 49.2 | Radiotherapy for urethral cancer | 541 |
| 49.3 | Chemotherapy | 546 |
| Pt. 8 | Urological Aspects of Gynecologic Malignancies | 547 |
| 50 | Overview of gynecologic malignancies | |
| 50.1 | Epithelial ovarian cancer | 549 |
| 50.2 | Cervical cancer | 553 |
| 50.3 | Uterine cancer | 558 |
| 51 | The role of exenteration and urinary diversion in gynecological malignancies | 563 |
| 52 | Management of urogynecologic fistulae | 571 |
| Pt. 9 | Common Pediatric Urologic Malignancies | 577 |
| 53 | Neuroblastoma | 579 |
| 54 | Wilms' tumor | 585 |
| 55 | Urologic manifestations of pediatric rhabdomyosarcoma | 591 |
| Pt. 10 | Patient Support and Palliative Care | 595 |
| 56 | Palliative care | 597 |
| Index | 617 |