| Contributors | |
| Pt. I | Primary Mediators of the Coping Response | |
| 1 | Synthesis, Storage, and Secretion of Adrenal Medullary Hormones: Physiology and Pathophysiology | 3 |
| 2 | Sympathetic Nervous System Physiology and Pathophysiology in Coping with the Environment | 21 |
| 3 | Catecholamines in the Brain and Responses to Environmental Challenges | 45 |
| 4 | Actions of Corticotropin on the Adrenal Cortex: Biochemistry and Cell Biology | 61 |
| 5 | Proopiomelanocortin Synthesis and Cell-Specific Processing | 85 |
| 6 | Regulation and Actions of Corticotropic-Releasing Hormone | 103 |
| 7 | Conticotropin-Releasing Factor in Brain: Executive Gating of Neuroendocrine and Functional Outflow | 125 |
| Pt. II | Fear, Stress, and Coping | |
| 8 | Coping with Danger: The Neural Basis of Defensive Behavior and Fearful Feelings | 139 |
| 9 | Neurobiology of Interpreting and Responding to Stressful Events: Paradigmatic Role of the Hippocampus | 155 |
| 10 | Chronic Stress and Energy Balance: Role of the Hypothalamo-Pituitary-Adrenal Axis | 179 |
| 11 | Adrenocortical Responses to Stress and their Modulation in Free-Living Vertebrates | 211 |
| Pt. III | Stress and Coping During the Life Course | |
| 12 | Development of the Hypothalamic-Pituitary-Adrenal Axis and the Stress Response | 237 |
| 13 | Development of Individual Differences in Behavioral and Endocrine Responses to Stress: Role of the Postnatal Environment | 271 |
| 14 | Mechanisms of Glucocorticoid Actions in Stress and Brain Aging | 293 |
| Pt. IV | Coping: Impact of Diurnal Rhythms and Sleep | |
| 15 | Roles of Sleep-Wake and Dark-Light Cycles in the Control of Endocrine, Metabolic, Cardiovascular, and Cognitive Function | 313 |
| 16 | Hormones, Cytokines, and Sleep | 331 |
| Pt. V | Stress, Coping, and Immune Defenses | |
| 17 | Regional Neural Regulation of Immunity: Anatomy and Function | 353 |
| 18 | Role of Endogenous Glucocorticoids in Immune System Function: Regulation and Counterregulation | 381 |
| 19 | Interactions between the Hypothalamic-Pituitary-Adrenal Axis and Immune System during Viral Infection: Pathways for Environmental Effects on Disease Expression | 425 |
| 20 | Regulation of Inflammatory Autoimmune Diseases | 451 |
| 21 | Immunophysiology: The Interaction of Hormones, Lymphohemopoietic Cytokines, and the Neuroimmune Axis | 469 |
| 22 | Environmental Factors and Disease: Stress and Cancer | 497 |
| Pt. VI | Stress, Coping, and the Social Environment | |
| 23 | Physiological and Pathophysiological Implications of Social Stress in Mammals | 517 |
| 24 | Social Ordering and Health | 533 |
| Index | 547 |