The Cytokine FactsBook - ISBN: 0121551423


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		"He felt about books as doctors feel about medicines, or managers about plays - cynical, but hopeful." - Rose Macaulay, Crewe Train, 1926

	The Cytokine FactsBook
	by Luke A. O'Neill, Katherine A. Fitzgerald, Andy J. Gearing

ZIN Product Number: 10018004

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Product Details

Format: Paperback, 2nd ed., 528 pages

Edition: 2ND

Publisher: Academic Press, Incorporated

ISBN: 0121551423

Release Date: Jan 9, 2001

Rating: 3 Stars from Doody

From The Publisher
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and structure? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?

The Academic Press FactsBook series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'A growing series of excellent manuals' by Molecular Medicine Today, and 'Essential works of reference' by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. Using the same easy-to-follow format, the new edition of The Cytokine FactsBook will keep you up-to-date with the latest advances, and provide you with all the facts at your fingertips. Meticulously researched and compiled by experts in the field, keeping abreast of developments has never been so easy!

The Second Edition of The Cytokine FactsBook has been completely revised, updated and expanded by over 100%. It is the most up-to-date reference manual for all well-characterised interleukins, cytokines and their receptors. Introductory chapters provide background information on the Cytokine Network and Cytokine Receptor Superfamilies. This is followed by over 100 comprehensive individual entries covering each cytokine/chemokine/growth factor. Information is also provided on Cytokine Standards and Protein Sequence Retrieval Database Servers, and Mouse Knockout Databases.

The Cytokine FactsBook now also includes free online access to the regularly updated Cytokine Webfacts. Cytokine Webfacts is a web-based comprehensive compendium of facts about cytokines and their receptors which includes a variety of data representations, such as text, signal pathway diagrams and 3-D images. This exciting resource is integrated into other databases via hypertext links to provide a unique network, and contains a web-enabled version of RasMol for viewing structures.

Annotation
"...chock-full of the elusive facts on cytokines, including information on cross reactivity, bio assays, 3-D structure, alternative nomenclature, receptors, signal transduction, chromosomal location of receptors, and references."

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Accreditation
Fitzgerald, Katherine A.; O'Neill, Luke A.J.; Gearing, Andy J.H.; Callard, Robin E.

	Preface	vii
	Abbreviations	viii
Section I	The Introductory Chapters
Chapter 1	Introduction	1
Chapter 2	Organization of the Data	8
Chapter 3	The Cytokine Network	12
Chapter 4	Cytokine Receptor Superfamilies	20
Section II	The Cytokines and Their Receptors
	Interleukins
	IL-1	35
	IL-2	44
	IL-3	51
	IL-4	58
	IL-5	64
	IL-6	69
	IL-7	75
	IL-8	80
	IL-9	85
	IL-10	90
	IL-11	95
	IL-12	99
	IL-13	105
	IL-14	111
	IL-15	113
	IL-16	116
	IL-17	119
	IL-18	123
	Other Cytokines and Chemokines (in alphabetical order)
	Activin	129
	Amphiregulin	136
	Angiostatin	139
	Apo2L	142
	APRIL	148
	BAFF	150
	4-1BBL	153
	BCA-1	157
	BDNF	160
	Betacellulin	166
	BMPs	168
	CD27L	174
	CD30L	178
	CD40L	183
	6Ckine	188
	CNTF	192
	CT-1	197
	CTACK	200
	EGF	203
	ELC	209
	ENA-78	211
	Eotaxin 1	213
	Eotaxin 2	217
	Eotaxin 3	219
	Epo	221
	Fas ligand	225
	FGF	230
	Flt3 ligand	244
	Fractalkine	249
	GCP-2	253
	G-CSF	255
	GDNF	260
	GITRL	267
	GM-CSF	270
	GRO[alpha], [beta] and [gamma] (MIP-2)	275
	Growth hormone	278
	HB-EGF	283
	HCC-1	286
	HCC-4	288
	HGF	290
	I-309	297
	IGF I and II	301
	IFN[alpha] and IFN[omega]	311
	IFN [beta]	319
	IFN[gamma]	322
	[gamma]IP-10	328
	ISG-15	332
	ITAC	335
	LARC	337
	Leptin	340
	LIF	346
	LIGHT	351
	Lptn	354
	LT (TNF[beta])	357
	MCP-1, -2, -3, -4 and -5	361
	M-CSF	367
	MDC	373
	MEC	377
	MIF	379
	MIG	382
	MIP-1[alpha]	384
	MIP-1[beta]	389
	MSP	392
	NGF	397
	NT-3	405
	NT-4	412
	OSM	415
	OX-40L	420
	PBP, CTAP-III, NAP-2 and [beta]TG	424
	PDGF (AA, AB, BB)	426
	PF-4	436
	Prolactin	439
	RANTES	444
	SCF	448
	SDF-1	453
	TARC	457
	TECK	460
	TGF[alpha]	464
	TGF[beta]	467
	TNF[alpha]	474
	Tpo	481
	TRANCE	486
	TSLP	490
	TWEAK	493
	VEGF	498
Appendix I	Cytokine Standards	505
Appendix II	WWW Sites for DNA and Protein Databases	507
Appendix III	Internet Resources for Transgenic and Targeted Mutation Research	508
	Index	509

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