| Contributors | |
| Preface | |
| Pt. 1 | Symptoms and Signs of Respiratory Disease | 1 |
| 1 | Approach to the Patient | 3 |
| 2 | Pulmonary Function and Cardiopulmonary Exercise Testing | 31 |
| 3 | Evaluation of Pulmonary Diseases by Imaging | 48 |
| 4 | Bronchoscopy, Transthoracic Needle Aspiration, and Related Procedures | 75 |
| 5 | Impairment and Disability Evaluation | 96 |
| Pt. 2 | Obstructive Lung Diseases | 103 |
| 6 | Chronic Obstructive Pulmonary Disease: Overview | 105 |
| 7 | Chronic Obstructive Pulmonary Disease: Epidemiology, Pathophysiology, Pathogenesis, Clinical Course, Management, and Rehabilitation | 118 |
| 8 | Asthma | 143 |
| 9 | Aspirin- and Exercise-Induced Asthma | 151 |
| 10 | Allergic Bronchopulmonary Aspergillosis and Hypersensitivity Reactions to Fungi | 159 |
| 11 | Upper Airway Obstruction | 165 |
| 12 | Cystic Fibrosis | 176 |
| 13 | Bronchiolitis | 187 |
| 14 | Bullous Diseases of the Lung | 198 |
| Pt. 3 | Occupational and Environmental Disorders | 203 |
| 15 | Occupational Lung Disorders: General Principles and Approaches | 205 |
| 16 | Asbestos-Related Lung Disease | 217 |
| 17 | Chronic Beryllium and Hard-Metal Lung Disease | 230 |
| 18 | Coal Workers' Lung Diseases and Silicosis | 238 |
| 19 | Occupational Asthma, Byssinosis, and Industrial Bronchitis | 250 |
| 20 | Toxic Inhalations | 257 |
| 21 | Indoor and Outdoor Air Pollution | 275 |
| 22 | Pulmonary Disorders Related to High Altitude | 285 |
| 23 | Diving Injuries and Air Embolism | 292 |
| 24 | Thermal Lung Injury and Acute Smoke Inhalation | 297 |
| Pt. 4 | Drug-Induced Lung Diseases | 307 |
| 25 | Drug-Induced Lung Disease due to Nonchemotherapeutic Agents | 309 |
| 26 | Pulmonary Toxicity Associated with Chemotherapeutic Agents | 327 |
| Pt. 5 | Interstitial and Inflammatory Lung Diseases | 337 |
| 27 | Interstitial Lung Disease: A Clinical Overview and General Approach | 339 |
| 28 | Systemic Sarcoidosis | 348 |
| 29 | Idiopathic Pulmonary Fibrosis | 360 |
| 30 | Hypersensitivity Pneumonitis | 373 |
| 31 | Radiation Pneumonitis | 381 |
| 32 | Pulmonary Manifestations of the Collagen Vascular Diseases | 390 |
| 33 | The Eosinophilic Pneumonias | 408 |
| 34 | Pulmonary Histiocytosis X | 423 |
| 35 | Pulmonary Lymphagioleiomyomatosis and Tuberous Sclerosis | 429 |
| 36 | The Lungs in Patients with Inborn Errors of Metabolism | 434 |
| Pt. 6 | Alveolar Diseases | 441 |
| 37 | Alveolar Hemorrhage Syndromes | 443 |
| 38 | Pulmonary Alveolar Proteinosis | 449 |
| Pt. 7 | Disorders of the Pulmonary Circulation | 451 |
| 39 | Pulmonary Hypertension and Cor Pulmonale | 453 |
| 40 | Pulmonary Thromboembolic Disease | 461 |
| 41 | Pulmonary Edema | 469 |
| 42 | Pulmonary Vasculitis | 477 |
| 43 | Pulmonary Arteriovenous Malformations | 482 |
| Pt. 8 | Disorders of the Pleural Space | 485 |
| 44 | Pleural Effusions: Nonmalignant and Malignant | 487 |
| 45 | Pneumothorax | 507 |
| 46 | Malignant Mesothelioma and Other Primary Pleural Tumors | 513 |
| Pt. 9 | Diseases of the Mediastinum | 519 |
| 47 | The Mediastinum: Overview, Anatomy, and Diagnostic Approach | 521 |
| Pt. 10 | Disorders of the Chest Wall and Neuromuscular Diseases | 535 |
| 48 | Disorders of the Chest Wall | 537 |
| 49 | Neuromuscular Diseases | 545 |
| Pt. 11 | Sleep and Sleep Disorders | 561 |
| 50 | Sleepiness, Control of Ventilation and Sleep-Disorders Breathing | 563 |
| Pt. 12 | Surgical Aspects of Pulmonary Medicine | 575 |
| 51 | Surgical Aspects of Pulmonary Medicine | 577 |
| 52 | Thoracic Trauma | 585 |
| 53 | Lung Transplantation | 593 |
| Pt. 13 | Neoplasms of the Lungs | 605 |
| 54 | The Solitary Pulmonary Nodule: A Systemic Approach | 607 |
| 55 | Non-Small Cell Lung Cancer - Clinical Aspects, Diagnosis, Staging, and Treatment | 615 |
| 56 | Lung Tumors Other Than Bronchogenic Carcinoma: Benign, Malignant, and Metastatic | 642 |
| 57 | Extrapulmonary Syndromes Associated with Lung Tumors | 652 |
| Pt. 14 | Infectious Diseases of the Lungs | 659 |
| 58 | Approach to the Patient with Pulmonary Infection | 661 |
| 59 | Antimicrobial Therapy of Common Pulmonary Infections | 700 |
| 60 | Community-Acquired Pneumonia | 715 |
| 61 | Nosocomial Respiratory Tract Infections and Gram-Negative Pneumonia | 734 |
| 62 | Mycobacterial Infections | 763 |
| 63 | Fungal Infections of the Lungs | 820 |
| 64 | Viral Infections of the Lungs and Respiratory Tract | 887 |
| 65 | Parasitic Infections of the Lungs | 912 |
| 66 | Pulmonary Infection in Immunocompromised Hosts | 941 |
| 67 | Zoonotic and Unusual Pneumonias | 997 |
| Pt. 15 | Acute Respiratory Failure | 1021 |
| 68 | Acute Respiratory Distress Syndrome | 1023 |
| 69 | Systemic Inflammatory Response and Multiple Organ Dysfunction Syndromes | 1029 |
| 70 | Acute Respiratory Failure in the Surgical Patient | 1034 |
| 71 | Respiratory Distress Syndrome of the Newborn | 1044 |
| 72 | Oxygen Therapy and Pulmonary Oxygen Toxicity | 1049 |
| 73 | Intubation and Upper Airway Management | 1058 |
| 74 | Hemodynamic and Respiratory Monitoring in Acute Respiratory Failure | 1064 |
| 75 | Mechanical Ventilation | 1073 |
| 76 | Nutrition in Acute Respiratory Failure | 1082 |
| 77 | Sedation and Analgesia in the Intensive Care Unit | 1090 |
| 78 | Pulmonary Pharmacotherapy | 1099 |
| 79 | Ethics in Critical Care | 1111 |
| App | Agents Potentially Associated with Bioterrorism | 1115 |
| Index | 1123 |