* Please Note: Traditional Use information is provided as a courtesy only. Although we have done our best to review the validity of these uses and we continue to revise this information as new data emerges, the traditional uses indicated on this page for this product may be wrong. This information is based on Traditional and Folklore Medicine which uses natural materials to support health. This information has not been evaluated or approved by the FDA and is not necessarily based on scientific evidence from any source. These statements have not been evaluated by the Food and Drug Administration (FDA). These products are intended to support general well being and are not intended to treat, diagnose, mitigate, prevent, or cure any condition or disease. If conditions persist, please seek advice from your medical doctor.
Other Names: Sanguinaire du Canada (French); Kanadische Blutwurzel (German); sanguinaria (Italian).
Description: Bloodroot is a small perennial herb (up to 0.4 m), producing a red sap or latex. It has solitary leaves and flowers emerging from a creeping, fleshy, red rhizome. The leaf has a rounded, markedly lobed blade. The attractive flower has four to 16 white petals and develops into a narrow, two-valved capsule containing numerous small seeds.
Origin: North America; mainly wild-harvested in the eastern parts of the USA.
Parts Used: Dried rhizome, with the roots removed (Sanguinariae canadensis rhizomza).
Uses and Properties: Traditionally used as an emetic, expectorant and spasmolytic to treat bronchitis and asthma, as well as other ailments of the respiratory tract (cough, croup, laryngitis and pharyngitis). In former times, it was applied topically against skin ulcers, warts and cancer. Despite its toxicity, bloodroot is still included in several commercial expectorants, cough syrups and stomachics. The most common modern use is as an ingredient of mouth rinses and toothpaste to counteract dental plaque and gingivitis.
Preparation and Dosage: Up to 0.5 g of dried rhizome is taken as an infusion (or equivalent extracts or tinctures) three times per day. The emetic dose is 1 - 2 g.
Active Ingredients: Isoquinoline alkaloids (up to 9%), with sanguinarine (a benzophenanthridine) as the main compound (about 50%) and several others including chelerythrine, sanguilutine, allocryptopine, protopine, berberine, coptisine.
Pharmacological Effects: The activity is ascribed mainly to sanguinarine. It intercalates DNA binds to proteins (including various receptors) and shows anti-inflammatory, antifungal, antimicrobial activity. It effectively inhibits dental plaque (as demonstrated in controlled clinical studies). The expectorant and emetic effect is probably due to the alkaloids (irritation of the nervus vagus).
Notes: Sanguinarine may also be obtained from the Asian plume poppy, Mackaya cordata.
Status: Traditional medicine; Pharm.; clinical studies+.
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Directions
Take 20-30 drops of extract in a small amount of warm water 3-4 times daily as needed.
Cautions
Not to be used during pregnancy and lactation. Do not exceed recommended dose.
Since sanguinarine and some of the other alkaloids can intercalate DNA, they are potential mutagens. There is new evidence that prolonged use in oral hygiene products may be harmful. *Note: Gylcerin-based liquid extracts of blood root are mild in strength and pose no known health risks..
Additional Information
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These statements have not been evaluated by the Food and Drug Administration (FDA). Products are intended to support general well being and are not intended to treat, diagnose, mitigate, prevent, or cure any condition or disease. If conditions persist, please seek advice from your medical doctor. The essence of the current American rule on Traditional Uses is, as stated by FTC, "Claims based on historical or traditional use should be substantiated by confirming scientific evidence, or should be presented in such a way that consumers understand that the sole basis for the claim is a history of use of the product for a particular purpose."
